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Mechanism of Action: When semaglutide binds to GLP-1 receptors, it stimulates the production of insulin while inhibiting the release of glucagon

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What I mean when I say that the hormones are a temporary solution is that another enzyme, known as Dipeptidyl Peptidase-4 (DPP-4), in the blood breaks down the hormones within 2-3 minutes of their release, thus rendering them inactive [5]