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Crucially, this study identified profound sex-specific differences in how this oxidative stress manifests
Wang et al., 2009, 2011), which could interact with behavioral measures of morphine tolerance
Glutathione (GSH) is a tripeptide molecule made from three amino acids: Cysteine (rate-limiting amino acid-contains sulfur) Glycine Glutamate It exists in two forms: Reduced glutathione (GSH) : Active form, the antioxidant Oxidized glutathione (GSSG) : Inactive form, created when GSH neutralizes free radicals The GSH:GSSG ratio is a critical marker of oxidative stress
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