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Dehydration and kidney function: Prolonged vomiting or diarrhoea can lead to dehydration and, in some cases, acute kidney injury

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For those who do not achieve glycemic targets with lifestyle therapy, metformin, and SGLT2i, or who cannot tolerate these agents, whether due to adverse events or because other restrictions apply, other medications are recommended

and by reducing adverse events often the #1 reason that patients stop using GLP-1 drugs Lexarias proprietary DehydraTECH technology could be of vital importance to any of these companies in their pursuit of the next oral GLP-1 drugs, the company explains