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Additionally, GLP-1RAs augment regulatory T cell (Treg) populations and elevate the levels of anti-inflammatory cytokines such as IL-10, contributing to immune tolerance and resolution of inflammation (26)

doi: 10.1136/gut.2005.079129 35 CvetkovicJ.Sofronic-MilosavljevicL.IlicN.GnjatovicM.NaganoI.Gruden-MovsesijanA

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While both medications are very effective weight loss options, it does appear that with time, patients on tirzepatide are losing more weight than semaglutide