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Treatment Options for Cobalt Allergy Managing cobalt allergy involves both avoiding exposure and treating symptoms
Registration clinical trials show that 16-37% of patients discontinue within a year (109111)
The current clinical evidence of intravenous glutathione for skin lightening is limited to a single study with a dubious study design and apparently flawed analysis of results, casting doubt on the drug's efficacy and reported adverse effects, with no evidence to prove its efficacy.There was only one placebo-controlled study on intravenous glutathione showing 37.5% response versus 18.7% placebo, and IV glutathione is contraindicated due to lack of efficacy and side effects
Emerging Therapies and Expanding Potential The research agenda just outlined assumes a relatively stable therapeutic landscape, one in which the primary task is generating better evidence for the combinations already in use
