Additionally, activated FLSs migrate to the synovial sub-lining layer to promote angiogenesis and exacerbate synovial hyperplasia and bone destruction [103]
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Interestingly, despite sharing mechanisms of induction and expression, tetanus-induced LTP was input-specific implying the need for presynaptic activation for the induction while LTP induced by AP trains was clearly independent of presynaptic activity at test synapses
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