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Theoretical considerations: Some researchers have raised theoretical concerns about GLP-1 effects on reproductive hormones, but clinical evidence of harm is lacking

In patients with other chronic liver diseases, such as viral hepatitis or alcohol-related liver disease, evidence is limited but early data suggest GLP1s may help reduce liver fat and improve liver enzymes

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Regular aerobic and resistance exercise for at least one hour per day, sleeping for at least 8 hours per night, stress reduction, discontinuation of all tobacco products and bioidentical hormone replacement therapy may decrease the rate of telomere loss