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In severe cases of dehydration, fainting or loss of consciousness can occur

Pathological manifestations of DPDs usually manifest macrovascular atherosclerosis, as well as microvascular endothelial function impairment, basement membrane thickening, and microthrombosis

Brains were dissected 4 h later, and c-Fos expression was assessed

Clinical Results and Safety Phase 2 clinical trials have reported encouraging weight loss outcomes, with participants receiving the highest doses achieving an average body weight reduction of approximately 24% over 48 weeks