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Switching to oral with variable absorption means those blood levels become unpredictable

28 note to investors, William Blair analysts wrote that Applied Therapeutics suspects the CRL was related to the efficacy package as opposed to [chemistry, manufacturing and controls] or safety. Results from the Phase III ACTION-Galactosemia Kids study, unveiled in April 2023, showed that govorestat fell short of its primary efficacy endpoint, a composite of four clinical measures designed to assess various domains of galactosemia symptoms

The medication may further reduce absorption of the small amounts obtained from fortified foods

Billing and coding: approved drugs and biologicals