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CYP2D6, MDMA, and methamphetamine: background considerations CYP2D6 accounts for only a small percentage of total hepatic cytochrome P450 (12%), yet it is responsible for the metabolism of approximately 2030% of marketed pharmaceuticals, including tricyclic antidepressants, selective serotonin reuptake inhibitor antidepressants, opioids, and antipsychotic, antiemetic, antiarrhythmic, and amphetamine-like drugs (Ingelman-Sundberg, 2005)

PMID: 14648529

It therefore raised the question of whether a high dietary intake of allulose may cause an undesirable growth advantage for potentially harmful bacteria at mucosal sites such as the intestine or at systemic sites following invasive infection

Histological examination of liver sections revealed ballooning degeneration in the GLP-1RA group, with no clear improvement compared to DB group (Fig