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Contemporary meta-analyses indicate that eicosapentaenoic acid-only therapy yields greater cardiovascular benefits than combinations of eicosapentaenoic acid and docosahexaenoic acid, despite comparable triglyceride reductions ( 2.3 Practical considerations The clinical application of high-dose omega-3 fatty acids is now guided by specific evidence and safety considerations

The efficacy of TCS in the diagnosis of PD has also been examined, but in 196 consecutive cases of clinically unclear parkinsonism, the diagnostic accuracy of TCS of substantia nigra in identifying early cases of PD could not be established (Bouwmans et al., 2013)

The panel responses to the consensus statements were synthesized into recommendations

The break is important: it allows the brain to consolidate the neuroplastic gains from the active phase and prevents receptor adaptation