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Inulin attenuates blood-brain barrier permeability and alleviates behavioral disorders by modulating the TLR4/MyD88/NF-kappaB pathway in mice with chronic stress

The ethosome gel not only significantly alleviated the OXA-induced mechanical allodynia and hyperalgesia but also decreased the numbers of eccentric nuclei of DRG neurons compared with rat model groups (Figures 3BD) ( FIGURE 3 Cerium oxide (CeO 2 ) NPs, where Ce as a rare chemical element can exist in two valence states (i.e., oxidized Ce 4+ and reduced Ce 3+ ), possess excellent ROS scavenging capability (like SOD and CAT enzymes) and relieve the oxidative stress in disease sites ( 2 NPs (60 mg/kg, i.p., daily for 4 weeks) offer protection against PIPN in rats since they significantly increased myelin protein zero (MPZ) expression, decreased the MDA levels, and reversed the histopathological changes in sciatic nerves and lumbar spinal cord caused by OXA

Le Roux 1

OCLC 1183789862