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8 celebrities who have spoken out about Ozempic, Hollywoods controversial weight-loss drug: from Sharon Osbourne and Oprah Winfrey to Sophie Turner, Amy Schumer and model Julia Fox Sharon Osbourne just spoke openly about her experience using Ozempic for weight loss a drug originally intended for diabetes sufferers and has warned others to be careful what you wish for Former Disney star Raven-Symon, activist Jameela Jamil, Padma Lakshmi, Game of Thrones star Sophie Turner and Amy Schumer all have strong opinions on the topic too heres what theyve said Sharon Osbourne is speaking out about her experience with Ozempic, as well as the drugs downsides