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The dosage escalation helps to reduce the risk of gastrointestinal side effects

Ryder SP, Oyelere AK, Padilla JL, Klostermeier D, Millar DP, Strobel SA (2001) Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping

However, it is best to keep consumption moderate, as ingredients such as caffeine and artificial sweeteners may affect sleep, digestion, or food cravings in some people

It may reduce dryness form the skin