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Early foundational biochemical work helped establish GHK as a biologically active copper-binding peptide involved in tissue repair environments: Comprehensive review of GHKs regenerative and matrix-related roles: Unlike synthetic growth factors, GHK is endogenous meaning it naturally occurs in the body which has contributed to long-term scientific interest

In two studies no detectable [100] or unchanged [101] activities of GSH peroxidase were found in spinal cord or cerebral cortex of ALS patients