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Particularly, we found the repression of lipogenic genes required a strong induction of NRF2 activity, as mild induction of NRF2 activity (0.510 11 pfu) was not sufficient to repress lipogenic gene expression

Once thyroxine treatment is initiated, it is required indefinitely in most patients

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Brayman and his team found that this therapy can retrain the immune system to ignore insulin-producing beta cells in mouse models of T1D, and he expanded on the mechanisms by which this happens