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The results revealed a significant reduction in ROS, HO, and MDA levels within the mouse skin, suggesting that grape seed PCs could effectively increase the antioxidant capacity of photoaged skin and delay the aging process

During perimenopause, estrogen levels start to decline, often fluctuating along the way, and continue to decrease throughout menopause, when estrogen levels reach their lowest point and remain low afterwards

For instance, if the activity of superoxide scavenging by SOD2 exceeds the capacity to remove the H2O2 generated, this oxidant can cause oxidative damage or be converted to other ROS

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