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For signs of infection at the injection site (rapidly spreading redness, warmth, swelling, or pus) or systemic symptoms such as high fever, chills, or feeling severely unwell, contact NHS 111 or attend an urgent treatment centre promptly
What the research shows: Chronic ipamorelin treatment increases the volume density of secretion granules in somatotroph cells and modulates intracellular GH content, demonstrating that sustained dosing produces cumulative pituitary-level changes rather than just transient GH spikes (Jimenez-Reina et al., 2002)
Notably, DPP-4 inhibitors appear to be safe regarding the risk of fractures, as they tend to decrease this risk, but more clinical trials are needed to explore the effects of DPP-4 inhibitors in other populations beyond T2DM