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10.1038/s41467-023-42382-4 Nat Commun

Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi -omics data integration

Rather than targeting an isolated cellular mechanism, this advanced 20,000mcg blend unifies two distinct synthetic peptide architectures: a stable gastric pentadecapeptide and a functional thymosin beta-4 fragment

To dissect the upstream regulatory mechanism of miR-29b-3p under Gln deprivation conditions, we integrated transcriptome data (GSE148016) from both Gln+ and Gln- groups, and performed cross-analysis with the predicted upstream transcription factors of miR-29b-3p, ultimately identifying five candidate transcription factors