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A phase 2, randomized, dose-finding study of the novel once-weekly human GLP-1 analog, Semaglutide, compared with placebo and open-label Liraglutide in patients with type 2 diabetes

Therefore, if a patient experiences severe or persistent burping, especially if accompanied by other symptoms like heartburn, nausea, or abdominal pain, further medical evaluation may be warranted

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This disrupts mitochondrial membrane potential (MMP), leading to mitochondrial dysfunction, mitophagy dysregulation, neuroinflammation, and subsequent dopaminergic neuronal degeneration (Meng et al., 2025)