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Description

Neutral loss patterns used to deduce lipid tail cleavages at Lys20

Differences between the two groups will be analyzed for statistical significance using the unpaired t test or MannWhitney U test for continuous data and Pearsons chi-square test or Fishers exact test for categorical data

Dysesthesia occurred in 22.9% of participants at the 7.2mg dose versus only 6% at the 2.4mg dose and 0.5% with placebo

Samples were centrifuged at 20,000 g , 4 C for 30 min, the supernatant transferred to a new tube, centrifuged again at 20,000 g , 4 C for 10 min, and the final supernatant transferred to a new 1.5 ml microtube