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Weight loss may also help lower blood pressure and improve cholesterol levels, which could decrease the risk of heart disease and other cardiovascular problems

Although the hypotensive effect of GLP-1 RAs seems to be manifested by BW losing, other mechanisms not related to BW might be implied by the mediation meta-analysis, which suggests an existence of BW-independent hypotensive effect of GLP-1 RA, along with the clinical evidence of weak or no correlations, and difference in time course between BP lowering and BW reducing effects

Permanent damage is unlikely unless you have overdosed, chronic use with liver compromise, or severe malnutrition

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