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It directly inhibits TGF-1/Smad signaling in HSCs, thereby reducing fibrosis and suppressing pro-inflammatory cytokines (TNF-, IL-6, IL-1) through the inhibition of the GPR120/NF-B pathway and modulation of the NLRP3 inflammasome

Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons

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In contrast to earlier findings in FM and other disorders, ALCAR did not