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In September 2025, the FDA issued over 50 warning letters to companies marketing compounded GLP-1 products with misleading claims

LegitScripts Data Reveals 1200% Increase in Violative and Problematic Advertisements for GLP-1 Medications Legitscript Has Seen Nearly a 100% Increase in New Applications for Its Healthcare Merchant Certification Program Year Over Year PORTLAND, Ore.--(BUSINESS WIRE)--Recent LegitScript data reveals the skyrocketing promotion of both GLP-1 medications and reported ads associated with selling compounded GLP-1 medications

The agency's position reflects growing concerns regarding product quality, patient safety, API sourcing practices, and marketing claims that may create confusion between FDA-approved therapies and compounded alternatives

Crucially, the principle of hormesis dictates that the benefits of hormetins are confined to a low-dose window