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It acts centrally via activation of the melanocortin-4 receptor (MC4R) in the hypothalamus

More Stable Blood Sugar Levels Soluble fiber (like the glucomannan in oats and psyllium husk) helps regulate blood sugar by slowing the absorption of glucose

Corticosteroids promote: Fat redistribution , causing central (truncal) obesity and the characteristic "cushingoid" appearance with prolonged use Fluid retention , leading to weight gain that may not reflect true fat accumulation but can be discouraging Muscle protein breakdown , reducing lean body mass and potentially lowering metabolic rate Insulin resistance , making weight loss more difficult The magnitude of these effects is generally dose- and duration-dependent