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Hayes RP, Schultz EM, Naegeli AN, Curtis BH

Additional context on medical indications and off-label questions is provided in our article on indications and off-label use for weight loss medications, even though naltrexone/bupropion itself does not belong to the group of GLP-1 agonists

ROS can further activate epithelial cells and macrophages facilitating neutrophil, monocyte, and lymphocyte recruitment, and the recruited activated inflammatory cells subsequently enhance additional ROS generation, increasing the pro-oxidant burden (8085)

Chavan RB, Lodagekar A, Shastri NR