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This isnt conclusive, but its an area of concern. Always speak with your healthcare provider before trying NAD supplements if you: We dont have long-term safety data related to most NAD supplements, Dr

[DOI] [PubMed] [Google Scholar] Yuan LQ, Xie H, Luo XH, Wu XP, Zhou HD, Lu Y, et al

3) Lu, Shelly C

Production of ATP is controlled by a group of intracellular proteins called the "mitochondrial respiratory chain complex." These proteins (referred to as complexes I-IV ) control enzymatic reactions that convert energy substrates like oxygen, carbohydrates, and fatty acids into ATP by way of a metabolic pathway called oxidative phosphorylation