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There is biological plausibility for pancreatic complications due to the supraphysiological stimulation of the pancreas, leading to hyperplasia

Methods We searched for eligible trials published in PubMed (last search in February 2015) by using the following search algorithm: (Glucagon-like peptide-1 receptor agonists OR exenatide OR liraglutide OR lixisenatide OR albiglutide OR dulaglutide) AND (side effects OR adverse effects OR safety OR gastrointestinal OR pancreas OR liver OR cardiovascular OR skin OR allergy OR angioedema OR immune system OR renal OR kidney OR infection OR central nervous system OR blood OR malignancy OR cancer) The search was limited by the following criteria: - Published in the English language

The medication's half-life of approximately one week allows for once-weekly subcutaneous administration, maintaining steady drug levels that provide consistent appetite suppression throughout the dosing interval

It's recommended