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Content is compiled from publicly available scientific literature and is intended to summarize current areas of research involving investigational compounds

10.1016/j.redox.2019.101335 37 SiesH

PXN inhibits phosphodiesterase 9 (PDE9), which terminates nitric oxide (NO) neurotransmission by metabolizing cyclic guanosine monophosphate (cGMP) back to GMP

[70] Immunotherapy targeting MET Drugs used for immunotherapy can act either passively by enhancing the immunologic response to MET-expressing tumor cells, or actively by stimulating immune cells and altering differentiation/growth of tumor cells