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The combination of GLP-1 receptor agonists with amylin analogues or future ghrelin receptor-targeting therapies may provide greater reductions in body weight and adiposity than monotherapy

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Gastrin is a neuroendocrine peptide, which acts on the cholecystokinin-2 (CCK2) receptor and is expressed in the pancreas with the rationale being that as it is involved in pancreas development, it might increase -cell mass and glycemic control [70]

Between-study heterogeneity was moderate (Q = 13.12, p = 0.157