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Extensive clinical trials have shown that GLP-1 receptor agonists can lead to significant, sustained weight loss in people with obesity or overweight, even if they do not have diabetes

Additionally, GLP-1 has been shown to enhance the proliferation and differentiation of endothelial progenitor cells through upregulation of VEGF, potentially promoting angiogenesis that could contribute to retinal complications [101,102]

This compound has gained significant attention within the scientific community for its unique receptor activity profile and ongoing research interest in controlled laboratory settings

Eli Lillys orforglipron, however, would be the first next-generation GLP-1 pill for weight loss if approved