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If you are planning a pregnancy or think you may be pregnant, contact your prescriber immediately before making any changes to your medication

Pregnancy and breastfeeding require medical advice before use

These include: Albright syndrome, a genetic disorder that can affect the skin and bones Congenital melanocytic nevus, a type of birthmark that appears at birth or in the first year of life Congenital smooth muscle hamartoma, a birthmark often present from birth or noticed in the first year of life Overdevelopment of certain pieces of tissue such as adrenal gland, limb, fingers, or toes Post-inflammatory hyperpigmentation, where skin becomes darker after it has been damaged Smooth muscle hamartoma, a rare, benign, skin growth often present at birth or in early infancy Underdevelopment of underlying structures such as the breast, body fat, limb, etc

They may not be uniformly immunoreactive for melanocyte differentiation antigens or even S100 protein