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In a study using 2.5 g of collagen peptides derived from bovine skin, along with minimal amounts of acerola extract, vitamins, and biotin, significant improvements in skin hydration, elasticity, roughness, and density were observed

Based on these reports, the impairment of synaptic function and synaptic transmission and the loss of synaptic density proteins are widely observed in the depressive brain ( Figure 2 )