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The only non-responder had HRS-CKD No recurrence during follow-up (mean 18 months)

Hasler F, Grimberg U, Benz MA, Huber T, Vollenweider FX

That approval status is a hard regulatory fact, and it is the single biggest reason a CagriSema-versus-tirzepatide comparison is not a comparison of equals: one product has cleared a full regulatory efficacy-and-safety review, and the other has not yet

Third, we chose to use overall survival as the primary endpoint, which is a hard outcome, providing a comprehensive assessment of the treatment effect in a retrospective study, although the proportion of patients becoming non-self-sufficient and ALSFRS-R total score, used as secondary outcomes, are validated endpoints for trials in ALS