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This variability likely reflects heterogeneity in the biological drivers of obesity across individuals, suggesting opportunity for precision medicine approaches that match patients to optimal therapeutic mechanisms
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These situations include when the prescriber demonstrates other failed weight loss treatments [and] sometimes when the BMI is over 30 or over 27 with weight-related chronic conditions like high blood pressure or sleep apnea. Still, she adds that most insurance companies are strict about covering medications solely for FDA-approved indications
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