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Activation of frataxin can enhance PINK1/Parkin-mediated mitophagy, which can significantly ameliorate lipid accumulation induced by a high-fat diet and free fatty acids [258, 259]

Can BPC-157 be combined with other peptides or therapies

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To generate the triple AA mutant with all three serine doublets mutated to alanine, the S441/2A mutant was used as a template to introduce serial alanine modifications at positions 451/452 and 444/445 using mutagenesis primers specifically designed to preserve the previous serine to alanine mutations