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[3] Common conditions like gastritis, anemia, and Crohn's disease can diminish your B12 levels

Class IA or III antiarrhythmics (that prolong the QT interval) may cause torsades de pointes with diuretic-induced hypokalemia

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While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control