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Definition and Medical Classification Semaglutide is classified as a glucagon-like peptide-1 (GLP-1) receptor agonist

Caution: Do not use if you are pregnant or breastfeeding or if you have a primary systemic L-carnitine deficiency or secondary L-carnitine deficiency (inborn errors in metabolism) for which levocarnitine supplementation is prescribed and/or monitored by a health care practitioner

doi: 10.1093/ajcn/nqy251 97

Key evidence supporting the notion came from the SELECT trial, which included 17,604 participants aged 45 and older from over 800 locations, recently demonstrated that weekly subcutaneous injections of 2.4 mg of semaglutide significantly reduced MACEs by 20% compared to a placebo in overweight and obese individuals with existing atherosclerotic CVD but no diabetes [26]