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Ma L, Fu Q, Xu B, Zhou H, Gao J, Shao X, Xiong J, Gu Q, Wen S, Li F, et al

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GLP-1GIP Coagonists: Improving Glycemic Control and Weight Loss While Reducing Nausea and Emesis Approximately 30 years ago, the discovery was made that a compound in the venom-laced saliva of the Gila monster shared properties similar to those of human GLP-1, but unlike the endogenous active form of GLP-1 [i.e., GLP-1(7-36)], this compound was resistant to enzymatic degradation by dipeptidyl peptidase IV