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BA, along with its downstream receptors farnesoid X receptor (FXR) and Takeda G protein-coupled receptor 5 (TGR5), plays an important role in lipid metabolism in the liver (78)

Effects of dietary fat and L-carnitine on plasma and whole blood taurine concentrations and cardiac function in healthy dogs fed protein-restricted diets

Since soluble DPP4 is characterized as an adipokine (4) and also correlates with parameters of the metabolic syndrome (5), it might also be an important molecular biomarker

Other factors that can be considered to be triggers can include skin damage, extreme and prolonged exposure to the sun, emotional distress, and exposure to certain chemicals