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Therefore, it is plausible to speculate that regaining the balance between the protective and detrimental mechanisms is a mainstay in the pharmacotherapy of PD

Results Our analysis revealed that the traditional logistic regression model outperforms the other machine learning models, with an area under the Receiver Operating Characteristic curve (auROC) of 0.77.Our model showed that higher pre-treatment HbA1C is a dominant feature for predicting better response to GLP-1 M, while features such as use of thiazolidinediones or sulfonylureas is correlated with poorer response to GLP-1 M, as assessed by lowering of hemoglobin A1C (HbA1C), a standard marker of glycated hemoglobin used for assessing glycemic control in individuals with diabetes

The NHS Eatwell Guide recommends including protein sources as part of a balanced diet alongside plenty of fruit and vegetables, some starchy carbohydrates, and smaller amounts of dairy (or alternatives) and healthy fats

Glp-1-R agonists have been also found to inhibit platelet activity ex vivo, and this mechanism can be considered as another cardioprotective factor [17]