Its application to deeper knee structures such as the joint capsule, ligaments, or cartilage in human patients remains largely theoretical at this stage
It involves weighing several critical factors, each with its own ripple effect on your research project: Research Goals and Endpoints: Are you looking for a sustained, moderate effect over a long period, or a rapid, potent peak concentration
This means that while its origin is rooted in a natural biological component, the compound itself is a manufactured entity, which has significant implications for its classification and oversight by regulatory bodies
As shown in Figure S7 , the niclosamide UV/Vis spectra from 25uM to 300uM all show the characteristic double peak profile at this pH of 9.3, with max maxima at 333nm and 377nm, although the maximum in aqueous pH 9.3 buffer was closer to 335nm