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It is accepted that an excessive burden of ROS may lead to abnormal cell growth, corresponding changes in intracellular homeostasis and damage to important components of in the cell when the antioxidant defense and/or DNA repair mechanisms cannot balance the excess oxidants [29]

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Male SD rats were administered a single IM injection of blank solvent (excipient), and biological samples, including whole blood, plasma, urine, feces, and tissues, were collected for background control

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