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Patients often experience reduced hunger and early satiety, creating risk for inadequate protein and micronutrient intake if dietary quality is poor
Kaiser Northwest, for example, requires: (1) documented diet and exercise program, (2) failure of at least 2 weight loss medications (phentermine, Qsymia, Contrave, etc.), AND (3) a minimum 6-month trial of semaglutide (Wegovy or Ozempic) that was ineffective or not tolerated
Upper abdominal pain, fever, jaundice, or clay-colored stools , which are listed as warning symptoms of gallbladder problems in Zepbound's medication guide
However, the 12mg maintenance dose still requires multiple draws or a 1mL+ syringe
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