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Long-term GLP-1 safety has been established through multi-year clinical trials showing benefits in cardiovascular outcomes and sustained weight management without cumulative toxicity

Unregulated or substandard formulations pose additional hazards, including contamination, inaccurate dosing, and compromised stability

From my point of view, this is a real do not try this at home scenario

Finally, the gut microbiome may contribute to NAFLD pathogenesis: an increased intestinal permeability could lead to the entry of endotoxins in portal circulation and activation, through toll-like receptor 4, of Kupffer cells, with consequent inflammation (5053)