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6-alpha-methylprednisolone (1 mg/kg intraperitoneally, once daily) was given alone which produced a considerable worsening and was completely eliminated with coadministration of BPC 157 10 g/kg intraperitoneally

In a 2014 study published in the Journal of Pharmacology and Experimental Therapeutics , Benoist and colleagues used the HGF/c-Met dimerization antagonist Hinge to block Dihexas effects in scopolamine-impaired rats, demonstrating that the procognitive activity requires functional hepatocyte growth factor (HGF) / mesenchymal-epithelial transition factor (c-Met) receptor signaling [3]

Helzner EP, Scarmeas N, Cosentino S, Tang MX, Schupf N, Stern Y

Int J Mol Sci (2020) 21:9234