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Yes, several lifestyle strategies can help increase GLP-1 naturally, including eating high-fiber foods, consuming adequate protein, maintaining a healthy gut microbiome, exercising regularly, and aligning meals with your circadian rhythm

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This partial reversal may be driven by factors such as compliance challenges, waning drug efficacy or measurement limitations

Therefore, to clarify whether the function of GLP-1R is activated or inhibited in CM, we detected the changes in the level of endogenous GLP-1, a natural agonist of GLP-1R, in the TNC in NTG-induced CM mice