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As expected, patients with active CD had a significantly lower red blood cell count and haemoglobin concentration in blood, higher platelets count and higher CRP level in serum compared with patients with inactive CD and controls

Research investigations reveal that senescent cells contribute to fibrosis through SASP-mediated inflammation, and their elimination can reduce fibrotic progression, providing researchers with tools for studying senescence contributions to fibrotic diseases and developing interventions for fibrosis research models

PMCID: PMC6910806.