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These metabolic benefits translate into whole-body effects: for example, in diet-induced obesity models, MOTS-c administration prevented excessive weight gain and insulin resistance when mice were fed a high-fat diet, without affecting weight in lean diets

Unhealthy brains consistently have lower glutathione and higher markers of oxidative stress

From there the Harding lab built a series of metabolically stabilized angiotensin IV analogs, including an antagonist called Norleual, before arriving at dihexa, a stable, brain-penetrant descendant engineered to last in the body and reach the brain

Intravenously, it is absorbed into your blood stream in its full strength, preventing the enzyme responsible of melanin production, and lowering oxidative stress at the cellular level