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While the 2025 Employer Health Benefit Survey finds there was a notable increase in the share of the largest firms (5,000+) that cover GLP-1 medications for weight loss, the conversations with employers highlight their concerns about the cost of these medications

Although a fairly large proportion of patients have reported a number of side effects, particularly at the gastrointestinal level (nausea, vomiting, diarrhoea), these side effects tend to diminish over time and adherence to treatment remains high, with about 5% of patients discontinuing treatment due to side effects

Dorian also shares his journey and transformation from wayward youth to world champion athlete, his exploration of psychedelics, views on cannabis and on longevity and health optimization more generally